Blog page 105



                                               

MIR494

microRNAs miRNAs are short 20-24 nt non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymer ...

                                               

MLH3

This gene is a member of the MutL-homolog MLH family of DNA mismatch repair MMR genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as ...

                                               

MMP14

Proteins of the matrix metalloproteinase MMP family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such ...

                                               

MNAT1

Cyclin-dependent kinases CDKs, which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase CAK. CAK is a multisubunit protein that includes CDK7 MIM 601955, cyclin H C ...

                                               

MOAP1

Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene. The protein encoded by this gene was identified through its interaction with regulators of the apoptosis protein BAX. This protein contains protein Bcl-2 homology ...

                                               

MPP5

MAGUK p55 subfamily member 5 is a protein that in humans is encoded by the MPP5 gene. Members of the peripheral membrane-associated guanylate kinase family function in tumor suppression and receptor clustering by forming multiprotein complexes co ...

                                               

MTHFD1

MTHFD1 is a gene located in humans on chromosome 14 that encodes for a protein with three distinct enzymatic activities. C-1-tetrahydrofolate synthase, cytoplasmic also known as C1-THF synthase is an enzyme that in humans is encoded by the MTHFD1 ...

                                               

MYH6

Myosin heavy chain, α isoform is a protein that in humans is encoded by the MYH6 gene. This isoform is distinct from the ventricular/slow myosin heavy chain isoform, MYH7, referred to as MHC-β. MHC-α isoform is expressed predominantly in human ca ...

                                               

NEMF (gene)

This gene encodes a component of the ribosome quality control complex. The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor supp ...

                                               

Neuroglobin

Neuroglobin is a member of the vertebrate globin family involved in cellular oxygen homeostasis. It is an intracellular hemoprotein expressed in the central and peripheral nervous system, cerebrospinal fluid, retina and endocrine tissues. Neurogl ...

                                               

NOVA1

RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. This gene encodes a neuron-specific RNA-binding protein, a member of the family, a new paraneoplastic disease antigens, that is recognized and inhibited paraneop ...

                                               

NRXN3

Neurexin-3-alpha is a protein that in humans is encoded by the NRXN3 gene. Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of w ...

                                               

NUMB (gene)

Protein numb homolog is a protein that in humans is encoded by the NUMB gene. The protein encoded by this gene plays an important role in determining the fate of cells during development. The encoded protein, whose degradation is induced in a pro ...

                                               

OR4E2

Olfactory receptor 4E2 is a protein that in humans is encoded by the OR4E2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4K1

Olfactory receptor 4K1 is a protein that in humans is encoded by the OR4K1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4K2

Olfactory receptor 4K2 is a protein that in humans is encoded by the OR4K2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4K5

Olfactory receptor 4K5 is a protein that in humans is encoded by the OR4K5 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4K13

Olfactory receptor 4K13 is a protein that in humans is encoded by the OR4K13 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR4K14

Olfactory receptor 4K14 is a protein that in humans is encoded by the OR4K14 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR4K15

Olfactory receptor 4K15 is a protein that in humans is encoded by the OR4K15 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR4K17

Olfactory receptor 4K17 is a protein that in humans is encoded by the OR4K17 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR4L1

Olfactory receptor 4L1 is a protein that in humans is encoded by the OR4L1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4M1

Olfactory receptor 4M1 is a protein that in humans is encoded by the OR4M1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4N2

Olfactory receptor 4N2 is a protein that in humans is encoded by the OR4N2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4N5

Olfactory receptor 4N5 is a protein that in humans is encoded by the OR4N5 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4Q3

Olfactory receptor 4Q3 is a protein that in humans is encoded by the OR4Q3 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR5AU1

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors GPCR arising fr ...

                                               

OR6S1

Olfactory receptor 6S1 is a protein that in humans is encoded by the OR6S1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR10G2

Olfactory receptor 10G2 is a protein that in humans is encoded by the OR10G2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR10G3

Olfactory receptor 10G3 is a protein that in humans is encoded by the OR10G3 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR11G2

Olfactory receptor 11G2 is a protein that in humans is encoded by the OR11G2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR11H4

Olfactory receptor 11H4 is a protein that in humans is encoded by the OR11H4 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OR11H6

Olfactory receptor 11H6 is a protein that in humans is encoded by the OR11H6 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor ...

                                               

OTUB2

Ubiquitin thioesterase OTUB2 is an enzyme that in humans is encoded by the OTUB2 gene. Otubains are deubiquitinating cysteine protease dubs, see MIM 602519 that belong to the ovarian tumors of the OTU superfamily of proteins. Like other dubs, otu ...

                                               

PABPN1

Polyadenylate-binding protein 2 also known as polyadenylate-binding nuclear protein 1 is a protein that in humans is encoded by the PABPN1 gene.

                                               

PAPOLA

Poly polymerase alpha is an enzyme that in humans is encoded by the PAPOLA gene. PAPOLA is associated with FIP1L1 factor interacting with PAPOLA and CPSF1, subunit of the cleavage and polyadenylation specificity factor subunit of complex 1 CPSF1. ...

                                               

PARP2

This gene encodes polyADP-ribosyltransferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a polyADP-ribosylation reaction. This protein has a catalytic domain which is homologous to that of poly ADP-ribosyl trans ...

                                               

PCNX

Pecanex-like protein 1 is a protein that in humans is encoded by the PCNX gene. The gene is found in Homo sapiens, and functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer.

                                               

Phosphoenolpyruvate carboxykinase

Phosphoenolpyruvate carboxykinase is an enzyme in the lyase family used in the metabolic pathway of gluconeogenesis. It converts oxaloacetate into phosphoenolpyruvate and carbon dioxide. It occurs in two forms, cytosolic and mitochondrial.

                                               

PIGH

Phosphatidylinositol N-acetylglucosaminyltransferase subunit H is an enzyme that in humans is encoded by the PIGH gene. The PIGH gene is located on the reverse strand of chromosome 14 in humans, and is neighbored by TMEM229B. This gene encodes an ...

                                               

PLEK2

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene. The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.

                                               

POMT2

POMT2 encodes an integral membrane protein of the endoplasmic reticulum ER that shares significant sequence similarity with a family of protein O-mannosyltransferases of S. cerevisiae. For additional background information, see POMT1 MIM 607423.

                                               

PPM1A

Protein phosphatase 1A is an enzyme that in humans is encoded by the PPM1A gene. The protein encoded by this gene is a member of the PP2C family of SER / Tr phosphatase protein. Members of the PP2C family are negative regulators of cell stress re ...

                                               

PPP1R13B

Apoptosis-stimulating of p53 protein 1 is a protein that in humans is encoded by the PPP1R13B gene. This gene encodes a member of the ASPP apoptosis-stimulating protein of p53 family proteins p53 interaction. The protein contains four ankyrin rep ...

                                               

PPP2R5C

The product of this gene belongs to the Protein phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consist ...

                                               

PPP2R5E

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a c ...

                                               

PRIMA1

PRiMA functions to organize acetylcholinesterase AChE into tetramers, and to anchor AChE at neural cell membranes. This is accomplished by the proline rich anchor domain PRAD of PRIMA1 which anchors the tetramer of AChE into the plasma membrane o ...

                                               

PRKCH

Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene. Protein kinases with PKC is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. The PK ...

                                               

Protein arginine methyltransferase 5

Protein arginine N-methyltransferase 5 is an enzyme that in humans is encoded by the PRMT5 gene. PRMT5 symmetrically dimethylates H2AR3, H4R3, H3R2, and H3R8 in vivo, all of which are linked to a range of transcriptional regulatory events. PRMT5 ...

                                               

Protein kinase D1

Members of the protein kinase D PKD family function in many extracellular receptor-mediated signal transduction pathways. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission o ...

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