Blog page 61



                                               

FBXO2

F-box only protein 2 is a protein that in humans is encoded by the FBXO2 gene. This gene encodes a member of f-box family protein, which is characterized by an approximately 40 amino acid sequence, f-field. F-box proteins are one of four subunits ...

                                               

FBXO6

F-box only protein 6 is a protein that in humans is encoded by the FBXO6 gene. This gene encodes a member of f-box family protein, which is characterized by an approximately 40 amino acid sequence, f-field. F-box proteins are one of four subunits ...

                                               

FBXO28

F-box only protein 28 is a protein that in humans is encoded by the FBXO28 gene. Members of the f-box protein family, such as FBXO28, are characterized by approximately 40-amino acid f-box motif. SCF complexes, formed by SKP1 MIM 601434, Callen t ...

                                               

FCER1G

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.

                                               

FCN3

Ficolin-3 is a protein that in humans is encoded by the FCN3 gene. Ficolin-3 was initially identified as H-ficolin, in which H is after the Hakata antigen that was previously found as an autoantigen in patients who lived in the city of Hakata. Fi ...

                                               

FCRL3

Fc receptor-like protein 3 is a protein that in humans is encoded by the FCRL3 gene. This gene encodes a member of the receptors of the superfamily of immunoglobulins and is one of several receptors like FC glycoproteins cluster on the long arm o ...

                                               

FCRL4

Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.

                                               

FCRLA

Fc receptor-like A is a protein that in humans is encoded by the FCRLA gene. Receptors for the FC fragment of IgG, or FCGRs to see MIM 146790, surface glycoproteins of cells igsf, IG superfamily. These receptors mediate the phagocytosis of IgG-co ...

                                               

Flavin containing monooxygenase 1

Dimethylaniline monooxygenase 1 is an enzyme that in humans is encoded by the FMO1 gene. Metabolic N-oxidation of the diet-derived amino-trimethylamine, TMA is mediated by plainstrasse of monooksigenazy and is to be inherited FMO3 polymorphism in ...

                                               

FMO2

Dimethylaniline monooxygenase 2 is an enzyme that in humans is encoded by the FMO2 gene. In the flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. Most mammals have plainstrasse ...

                                               

FMO4

Metabolic N-oxidation of the diet-derived amino-trimethylamine TMA is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity res ...

                                               

FMO5

Dimethylaniline monooxygenase 5 is an enzyme that in humans is encoded by the FMO5 gene. Metabolic N-oxidation of the diet-derived amino-trimethylamine, TMA is mediated by plainstrasse of monooksigenazy and is to be inherited FMO3 polymorphism in ...

                                               

FNBP1L

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin c ...

                                               

FOXD3

This gene belongs to the forkhead protein family of transcription factors which is characterized by a DNA-binding forkhead domain. FoxD3 functions as a transcriptional repressor and contains the C-terminal engrailed homology-1 motif eh1, which pr ...

                                               

FPGT

Fucose-1-phosphate guanylyltransferase is an enzyme that in humans is encoded by the FPGT gene. L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many functional roles of these macromolecules, su ...

                                               

Fumarase

Fumarase is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle, and the cytosolic isoenzyme is ...

                                               

GADD45A

This gene is a member of a group of genes, the GADD45 genes, whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents mutagens. The DNA damage-induced transcription of this gene is ...

                                               

Galectin-8

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differ ...

                                               

GALNT2

Polypeptide N-acetylgalactosaminyltransferase 2 is an enzyme that in humans is encoded by the GALNT2 gene. This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-a ...

                                               

GAS5

Growth arrest-specific 5 is a non-protein coding RNA that in humans is encoded by the GAS5 gene. ГАЗА5 non-coding RNA, which accumulates in the stop of cell growth, acts as a decoy hormone response element for the glucocorticoid receptor GR and t ...

                                               

GBP1

Interferon-induced guanylate-binding protein 1 is a protein that in humans is encoded by the GBP1 gene. It belongs to the dynamin superfamily of large GTPases.

                                               

GBP2

Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene. GBP2 is a gene related to the superfamily of large GTPases which can be induced mainly by interferon gamma.

                                               

GCLM

Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, the first rate limiting enzyme of glutathione synthesis. The enzyme ...

                                               

GGPS1

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate GGPP synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an impor ...

                                               

GLMN

Glomulin is a protein that in humans is encoded by the GLMN gene. This gene encodes a phosphorylated protein that is a member of the Skp1-Callen-f-box complex. Protein is essential for the normal development of the vasculature and mutations in th ...

                                               

GLRX2

Glutaredoxin 2 is an enzyme that in humans encoded by the GLRX2 gene. GLRX2, also known as GRX2, is a glutaredoxin family protein and a thiol-disulfide oxidoreductase that maintains cellular thiol homeostasis. This gene consists of four exons and ...

                                               

Glucocerebrosidase

β-Glucocerebrosidase is an enzyme with glucosylceramidase activity that is needed to cleave, by hydrolysis, the beta-glucosidic linkage of the chemical glucocerebroside, an intermediate in glycolipid metabolism that is abundant in cell membranes. ...

                                               

GLUT1

Glucose transporter 1, also known as solute carrier family 2, facilitated glucose transporter member 1, is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of ...

                                               

Glutamine synthetase

Glutamine synthetase is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate пн3 ATP → glutamine ADP phosphate Glutamine synthetase uses ammonia ...

                                               

Glutathione S-transferase Mu 1

Cytosolic and membrane-bound forms of glutathione S -transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S -transferases have been identified: alpha, kapp ...

                                               

Glyceronephosphate O-acyltransferase

Glyceronephosphate O-acyltransferase is an enzyme associated with Rhizomelic chondrodysplasia punctata type 2. GNPAT is located on chromosome 1 on the plus strand. Gene C1orf131 is directly in front of him, and the nearest gene in the Lower EXOC8.

                                               

Glycogen debranching enzyme

A debranching enzyme is a molecule that helps facilitate the breakdown of glycogen, which serves as a store of glucose in the body, through glucosyltransferase and glucosidase activity. Together with phosphorylases, debranching enzymes mobilize g ...

                                               

GMEB1

This gene is a member of KDWK gene family. The product of this gene associates with GMEB2 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation ...

                                               

GNAT2

Transducin is a 3-subunit guanine nucleotide-binding protein G protein which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. Thi ...

                                               

GNB1

Heterotrimeric guanine nucleotide-binding proteins G proteins, which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This g ...

                                               

GON4L

GON-4-like protein is a protein that in humans is encoded by the GON4L gene. It is a nuclear protein containing two serine phosphosites and a lysine-glutamine cross-link and is thought to be a transcription factor.

                                               

GORAB

RAB6-interacting golgin also known as N-terminal kinase-like-binding protein 1 or SCY1-like 1-binding protein 1 is a protein that in humans is encoded by the GORAB gene.

                                               

GPA33

Cell surface A33 antigen is a protein that in humans is encoded by the GPA33 gene. The protein encoded by this gene is a surface antigen of cells, which is expressed in more than 95% of cases of colon cancer person. The open reading frame encodes ...

                                               

GPSM2

G-protein-signaling modulator 2, also called LGN for its 10 Leucine-Glycine-Asparagine repeats, is a protein that in humans is encoded by the GPSM2 gene.

                                               

Granulocyte colony-stimulating factor receptor

The granulocyte colony-stimulating factor receptor also known as CD114 is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor. The G-CSF receptors belongs to a fa ...

                                               

Gremlin (protein)

Gremlin1, previously known as Drm, is a highly conserved 20.7-kDa, 184 amino acid glycoprotein part of the DAN family and is a cysteine knot-secreted protein. Gremlin1 was first identified in differential screening as a transcriptional down-regul ...

                                               

GSTM3

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, ...

                                               

Guanylate cyclase activator 2B

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of ...

                                               

H3F3A

Histone H3.3 is a protein that in humans is encoded by the H3F3A gene. Histones-basic nuclear proteins that are responsible for the structure of the nucleosomes of the chromosomal fiber in eukaryotes. Two molecules each of four core histones form ...

                                               

H6PD

There are two forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form ...

                                               

HAX1

HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to be associated with T1, a substrate of src family tyrosine kinases. It also interacts with the product of PKD2 gene, ...

                                               

Hemojuvelin

Hemojuvelin, also known as repulsive guidance molecule C or hemochromatosis type 2 protein, is a membrane-bound and soluble protein in mammals that is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a seve ...

                                               

Hepatoma-derived growth factor

Hepatoma-derived growth factor also known as high mobility group protein 1-like 2 is a protein that in humans is encoded by the HDGF gene.

                                               

Herpesvirus entry mediator

Herpesvirus entry mediator, also known as tumor necrosis factor receptor superfamily member 14, is a human cell surface receptor of the TNF-receptor superfamily.

                                               

HHAT

Hedgehog acyltransferase, also called skinny hedgehog homology in humans, is a human gene. HHAT gene encodes an enzyme that catalyzes that often plays a regulatory role of the N-terminal of Sonic hedgehog. Mutations in HHAT produce a phenotype th ...

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