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DBN1

Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein is believed to play a role in the growth process of neurons. He is a member of the drebrin family of proteins ...

DCP2

mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene. DCP2 is a key component of an mRNA-decapping complex required for removal of 5-Prime cap from mRNA prior to its degradation from the 5-Prime end Fenger-Gron et al. 2005.

DDX41

Probable ATP-dependent RNA helicase DDX41 is an enzyme that in humans is encoded by the DDX41 gene. Dead box proteins, characterized by conservative motif ASP-STU-Ala-ASP, dead putative RNA helicase. They are involved in a number of cellular proc ...

DDX46

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp DEAD, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA ...

DEPDC1B

DEP Domain Containing Protein 1B also known as XTP1, XTP8, HBV XAg-Transactivated Protein 8, is a human protein encoded by a gene of similar name located on chromosome 5. DEPDC1B exact function is currently unknown. Profiles of expression suggest ...

DHX29

This gene encodes a member of the DEAH Asp-Glu-Ala-His subfamily of proteins, part of the DEAD Asp-Glu-Ala-Asp box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanni ...

DIAPH1

This gene is a homolog of the Drosophila diaphanous gene and belongs to the protein family of the formins, characterized by the formin homology 2 FH2 domain. It has been linked to autosomal dominant, fully penetrant, nonsyndromic low-frequency pr ...

DNAH5

Dynein heavy chain 5, axonemal is a protein that in humans is encoded by the DNAH5 gene. DNAH5 gene is protein-coding genes. 1 it provides instructions for synthesizing protein that belongs to the microtubule-associated protein complex made of he ...

Dock2

Dock2, also known as DOCK2, is a large protein involved in intracellular signalling networks. It is a member of the DOCK-A subfamily of the DOCK family of guanine nucleotide exchange factors which function as activators of small G proteins. Dock2 ...

Dopamine receptor D1

Based upon Northern blot and in situ hybridization, DRD1 mRNA expression in the central nervous system is highest in the dorsal striatum caudate and putamen and ventral striatum nucleus accumbens and olfactory tubercle. Lower levels of DRD1 mRNA ...

DUSP1

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and wh ...

EBF1

Transcription factor COE1 is a protein that in humans is encoded by the EBF1 gene. EBF1 stands for Early B-Cell Factor 1. EBF1 controls the expression of key proteins required for cell differentiation, signal transduction and function. A crucial ...

EDIL3

The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.

EIF4EBP3

This gene encodes a member of the EIF4EBP family which derives its name from proteins that bind to eukaryotic initiation factor 4E and that prevent its assembly into EIF4F. Co-transcription of this gene and the neighboring upstream gene MASK gene ...

Elongation factor for RNA polymerase II 2

Elongation factor for RNA polymerase II 2 is a protein that in humans is encoded by the ELL2 gene. The encoded protein is a component of the superelongation complex SPK, and drives the synthesis of immunoglobulins in plasma cells. Variations in t ...

Ephrin A5

Ephrin A5 is a protein that in humans is encoded by the EFNA5 gene. Ephrin-A5 is a glycosylphosphatidylinositol GPI-anchored protein of the ephrin-a subclass ephrin ligands, which binds EAZ subclass of Eph receptors. Ephrin-A5 has also been shown ...

ERAP1

Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, also known as endoplasmic reticulum aminopeptidase 1, is a protein which in humans is encoded by the ARTS-1 gene. Endoplasmic reticulum amino peptidase 1 operates in the end ...

ERAP2

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex MHC class I molecules rely on aminopeptidases such as ERAP1 and LRAP to trim precursors to antigenic peptides in the endoplasmic ...

ERCC8 (gene)

DNA excision repair protein ERCC-8 is a protein that in humans is encoded by the ERCC8 gene. This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B CSB and P44 proteins, and subunits of RNA polymerase II transcriptio ...

ESM1

Endothelial cell-specific molecule 1 is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells of the human lungs and the tissues of the kidneys. The expressio ...

Excitatory amino acid transporter 1

Excitatory amino acid transporter 1 is a protein that, in humans, is encoded by the SLC1A3 gene. EAAT1 is also often called the GLutamate ASpartate Transporter 1. EAAT1 is predominantly expressed in the plasma membrane that allows the removal of ...

EXOC3

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component prote ...

FABP6

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 the liver fatty acid ...

Factor XII

Coagulation factor XII, also known as Hageman factor, is a plasma protein. It is the zymogen form of factor XIIa, an enzyme of the serine protease class. In humans, factor XII is encoded by the F12 gene.

FAM114A2

FAM114A2 is a gene on chromosome 5 in humans that encodes a protein FAM114A2. The protein function is not well known. FAM114A2 is, however, highly conserved in mammals with homologs both in fungi and plants.

Fas associated factor family member 2

The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis AD, compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophi ...

FBXL7

F-box/LRR-repeat protein 7 is a protein that in humans is encoded by the FBXL7 gene. This gene encodes a member of f-box family protein, which is characterized by an approximately 40 amino acid sequence, f-field. F-box proteins are one of four su ...

FBXO4

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin ligase complex called SCFs SKP1-cullin-F-box ...

FBXW11

βTrCP2 is a protein that in humans is encoded by the FBXW11 gene. This gene encodes a member of f-box family protein, which is characterized by an approximately 40 residue structural motif, the f-box. F-box proteins are one of four subunits of ub ...

FGF1

FGF1, also known as acidic fibroblast growth factor, is a growth factor and signaling protein encoded by the FGF1 gene. It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein. Fibroblast growt ...

FGF10

The protein encoded by this gene is a member of the fibroblast growth factor FGF family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic developme ...

FGF18

Fibroblast growth factor 18 is a protein that in humans is encoded by the FGF18 gene. The protein encoded by this gene is a member of a family of fibroblast growth factor FGF. The FGF family members possess broad mitogenic and survival activities ...

Forkhead box d1

Forkhead box D1 is a protein that in humans is encoded by the FOXD1 gene. Forkhead d1 is a kidney expressed transcription factor maps at the chromosome 5 at position 5q12 - q13, identified in Drosophila forkhead protein and mammalian HNF3 transcr ...

FOXI1

Forkhead box I1 is a protein that in humans is encoded by the FOXI1 gene. This gene belongs to the forkhead family of transcription factors which is characterized by a special forkhead domain. The specific function of this gene has not yet been d ...

FYB

FYN binding protein, also known as FYB, ADAP, and SLAP-130 is a protein that in humans is encoded by the FYB gene.

G3BP1

Ras GTPase-activating protein-binding protein 1 is an enzyme that in humans is encoded by the G3BP1 gene. This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA / DNA ...

Gem-associated protein 5

Gem-associated protein 5 is part of the SMN a large protein complex localized to both the cytoplasm and the nucleus that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins snRNPs. Other members of this complex include SM ...

Geranylgeranyltransferase type 1

Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins be ...

GFRA3

The protein encoded by this gene is a glycosylphosphatidylinositolGPI-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

GRK6

This gene encodes a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinase family, and is most highly similar to GRK4 and GRK5. The protein phosphorylates the activated forms of G protein-coupled receptors to regu ...

Growth hormone receptor

This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to reorientation of a pre-assembled receptor dimer dimerization the receptor may however also exist as monomers on th ...

Growth hormone-binding protein

Growth hormone-binding protein is a soluble carrier protein for growth hormone. The function of GHBP is still unknown. Current research suggests that the protein is associated with regulation of the GH supply in the circulatory system as well as ...

GZMA

Granzyme A is a protein that in humans is encoded by the GZMA gene, and is one of the five granzymes encoded in the human genome. Cytolytic T-lymphocytes CTLs and natural killer NK-cells share the remarkable ability to recognize, bind, and lyse s ...

GZMK

Granzyme K is a protein that in humans is encoded by the GZMK gene. This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T-lymphocytes CTLs and natural killer NK-ce ...

H2AFY

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the fou ...

HARS

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl tRNA synthetases. The enzyme is respons ...

HARS2

Probable histidyl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the HARS2 gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene enzyme ...

HAVCR1

Hepatitis A virus cellular receptor 1 also known as T-cell immunoglobulin and mucin domain 1 is a protein that in humans is encoded by the HAVCR1 gene. It is also known as Kim-1 molecule kidney injury-1, which is a protein most strongly upregulat ...

HAVCR2

Hepatitis A virus cellular receptor 2, also known as T-cell immunoglobulin and mucin-domain containing-3, is a protein that in humans is encoded by the HAVCR2 gene. HAVCR2 was first described in 2002 as a cell surface molecule expressed on IFNγ p ...

HDAC3

Histones are highly alkaline proteins that package and order DNA into structural units called nucleosomes, which comprise the major protein component of chromatin. The posttranslational and enzymatically mediated lysine acetylation and deacetylat ...

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HEXB

Hexosaminidase

HINT1

Histamine H2 receptor

Hyaluronan-mediated motility receptor

Interleukin-7 receptor

Leucyl-tRNA synthetase

Leukotriene C4 synthase

Metabotropic glutamate receptor 6

Na-K-Cl cotransporter

Oncostatin M receptor

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