Blog page 72



                                               

POPDC2

This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle. The Popeye domain, which is located in the cy ...

                                               

PPP2R3A

Serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha is an enzyme that in humans is encoded by the PPP2R3A gene. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and is implicated in the negative control o ...

                                               

Prickle planar cell polarity protein 2

This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epil ...

                                               

PRKAR2A

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent Protein Kinase, more commonly called Protein Kinase A PKA, which transduces the signal through phosphorylation of ...

                                               

PRKCD

Protein kinase C PKC is a family of serine- and threonine-specific protein kinases that can be activated by the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in di ...

                                               

PRKCI

This gene encodes a member of the protein kinase C PKC family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This ...

                                               

Propionyl-CoA carboxylase

Propionyl-CoA carboxylase catalyses the carboxylation reaction of propionyl CoA in the mitochondrial matrix. The enzyme is biotin-dependent. The product of the reaction is -methylmalonyl CoA. Propionyl CoA is the end product of metabolism of odd- ...

                                               

Proser1

PROSER1 is located on the negative reverse strand of chromosome 13 at position 13q13.3. It spans from 39.009.865 base pairs from the pter to 39.038.095 bp from the pter, with a size of 28.231 bases. PROSER1 has a total of 13 exons in its primary ...

                                               

Protein S

Protein is a vitamin K-dependent plasma glycoprotein synthesized in the liver. In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein. In humans, protein is encoded by the ...

                                               

PSMD2

26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1, is an enzyme that in humans is encoded by the PSMD2 gene.

                                               

PSMD6

The proteasome and its subunits are of clinical significance for at least two reasons: 1 a compromised complex assembly or a dysfunctional proteasome can be associated with the underlying pathophysiology of specific diseases, and 2 they can be ex ...

                                               

PTPRG

Receptor-type tyrosine-protein phosphatase gamma is an enzyme that in humans is encoded by the PTPRG gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase family PTP. PTPS it is known that signaling molecules that ...

                                               

PTX3

Pentraxin-related protein PTX3 also known as TNF-inducible gene 14 protein is a protein that in humans is encoded by the PTX3 gene. Pentraxin 3 ptx3 is a member of the pentraxin superfamily. This is a super family characterized by a cyclic multim ...

                                               

QARS

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the f ...

                                               

RAB5A

RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to late endosomes. It drives the maturation of endosomes by transporting vacuolar H+-ATPases V-ATPases from trans-Golgi n ...

                                               

RAB7A

Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAS-related protein RAB-7a is involved in the endocytosis, which is a process that brings substances into the cell. The process of endocytosis of works by foldin ...

                                               

RAP2B

Ras-related protein Rap-2b is a protein that in humans is encoded by the RAP2B gene. RAP2B belongs to the Ras-related protein family. This intronless gene belongs to the family of RAS-related genes. The proteins encoded by these genes share about ...

                                               

RARRES1

Retinoic acid receptor responder protein 1 is a protein that in humans is encoded by the RARRES1 gene. This gene was identified as a retinoic acid receptor RA-responsive gene. It encodes a type 1 membrane protein. The expression of this gene are ...

                                               

Ras p21 protein activator 2

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein ...

                                               

RASSF1

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivati ...

                                               

RBM6

RNA-binding protein 6 is a protein that in humans is encoded by the RBM6 gene. RBM6 orthologs have been identified in all mammals for which complete genome data are available.

                                               

RFC4

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen PCNA and replication factor C RFC. RFC, also named activator 1, is a protein complex cons ...

                                               

RFT1

Protein RFT1 homolog is a protein that in humans is encoded by the RFT1 gene. Defects associated with congenital defect of glycosylation type 1H.

                                               

RNF7

RING-box protein 2 is a protein that in humans is encoded by the RNF7 gene. The protein encoded by this gene is a highly conserved protein finger ring. This is the most important unit of SKP1-Callen / CDC53-F box protein ubiquitin ligase, which a ...

                                               

RNF13

RING finger protein 13 is a protein that in humans is encoded by the RNF13 gene. The protein encoded by this gene contains a zinc finger ring, a well-known motive to be involved in protein-protein interactions. The specific function of this gene ...

                                               

RNF123

E3 ubiquitin-protein ligase RNF123 is an enzyme that in humans is encoded by the RNF123 gene. The protein encoded by this gene contains a ring motif is present in many functionally distinct proteins and participates in protein-protein and protein ...

                                               

RPL22L1

eL22L1 is a ribosomal protein paralog of the eL22 protein of the 60S ribosomal subunit. This paralog is divergent from the normal copy, and is expressed when the normal copy is deleted from mice. Such a compensation implies a role in ribosome fun ...

                                               

RPN1

Dolichyl-diphosphooligosaccharide - protein glycosyltransferase subunit 1 is an enzyme that in humans is encoded by the RPN1 gene. This gene encodes an integral membrane protein ribophorin I is a type found only in the rough endoplasmic reticulum ...

                                               

RPTOR

Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. Two mRNAs from the gene have been identified that encode proteins of 1335 and 1177 amino acids long.

                                               

RuvB-like 1

RuvB-like 1, also known as RUVBL1 and TIP49, is a human gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with RUVBL2 protein. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase activity, hexamerization ...

                                               

SATB1

SATB1, the global chromatin organizer and transcription factor, has emerged as a key factor integrating higher-order chromatin architecture with gene regulation. Recent studies have unraveled the role of SATB1 in organization of chromatin loopsca ...

                                               

SEC13

Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene. The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarities with yeast SEC13 and SEC31 proteins, which are required for ve ...

                                               

SEC22A

Vesicle-trafficking protein SEC22a is a protein that in humans is encoded by the SEC22A gene. The protein encoded by this gene belongs to the members of the SEC22 family of vesicle proteins people. This protein has similarity to rat SEC22 and may ...

                                               

Sec61 alpha 1

Protein transport protein Sec61 subunit alpha isoform 1 is a protein that in humans is encoded by the SEC61A1 gene. The protein encoded by this gene belongs to the SECY / SEC61 - alpha family. It seems to play an important role in the insertion o ...

                                               

SEC62

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum ER membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is spec ...

                                               

SELT

The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence SECIS, that is necessary for the recognition of UGA as a ...

                                               

SEMA3B

The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a ...

                                               

SEMA3F

Semaphorin-3F is a protein that in humans is encoded by the SEMA3F gene. In the semaphorins are a family of proteins involved in signaling. All family members have a secretion signal, a 500-amino acid domain of SEMA and 16 conservative cysteine r ...

                                               

SENP2

SUMO1 UBL1, MIM 601912 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUM ...

                                               

SERPINI1

Neuroserpin is a protein that in humans is encoded by the SERPINI1 gene. This is due to the family encephalopathy with neuroserpin inclusion bodies. Inhibitors of serine proteases of the Serpin superfamily are involved in many cellular processes. ...

                                               

SERPINI2

The protein encoded by this gene is a member of the serine protease inhibitor serpin superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, dev ...

                                               

SETD2

SETD2 protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been foun ...

                                               

SETD5

Model organisms have been used in the study of SETD5 function. A conditional knockout mouse line called Setd5 tm1aEUCOMMWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen ...

                                               

SETMAR

SETMAR contains a SET domain that confers its histone methyltransferase activity, on Lys-4 and Lys-36 of Histone H3, both of which are specific tags for epigenetic activation. It has been identified as a repair protein as it mediates dimethylatio ...

                                               

SFMBT1

This gene shares high similarity with the Drosophila Scm sex comb on midleg gene. It encodes a protein which contains four malignant brain tumor repeat mbt domains and may be involved in antigen recognition.

                                               

SGEF

SGEF is a 97 kDa protein involved in intracellular signalling networks. It functions as a guanine nucleotide exchange factor for RhoG, a small G protein of the Rho family.

                                               

SGOL1

Model organisms have been used in the study of SGOL1 function. A conditional knockout mouse line, called Sgol1 tm1aEUCOMMWtsi has been generated. Male and female animals underwent a standard screen to determine the phenotypic consequences of the ...

                                               

SIAH2

This gene encodes a protein that is a member of the seven in absentia homolog SIAH family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin liga ...

                                               

SIDT1

The protein encoded by this gene belongs to SID1 family of transmembrane dsRNA-gated channels. Family members transport dsRNA into cells and are required for systemic RNA interference.

                                               

SLC6A20

Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup ...

Free and no ads
no need to download or install

Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

online intellectual game →