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Major histocompatibility complex, class II, DP alpha 1

The protein encoded by this gene belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha DPA and a beta chain DPB, both anchored in the membrane. It plays a central role in the immune syst ...

MAK (gene)

Serine/threonine-protein kinase MAK is an enzyme that in humans is encoded by the MAK gene. The product of this gene is a serine / threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively i ...

MAN1A1

Mannosyl-oligosaccharide 1.2-alpha-mannosidase IA is an enzyme that in humans is encoded by the MAN1A1 gene. This gene encodes a class I mammalian Golgi 1.2-mannosidase, which is a type II transmembrane protein. This protein catalyzes the removal ...

Mannose 6-phosphate receptor

The mannose 6-phosphate receptors are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates. Mannose-6-phosphate receptors bind newly synthesized lysosomal hydrolases in the TRANS-Golgi network TGN and deliver them to pre-ly ...

MAP3K4

Mitogen-activated protein kinase 4 is an enzyme that in humans is encoded by the MAP3K4 gene. The Central core of each mitogen-activated protein kinase mark way is a conserved cascade of 3 protein kinases: an activated kinase Map-Kinas cascade MA ...

MAP3K7

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates signal transduction induced by TGF beta and morphogenetic protein BMP, and controls a variety of cell functions including transcripti ...

MAP3K7IP2

Mitogen-activated protein kinase 7-interacting protein 2 is an enzyme that in humans is encoded by the MAP3K7IP2 gene. The protein encoded by this gene is an activator of MAP3K7 / TAK1, which is required for Il-1 induced activation of nuclear fac ...

MAP7

The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarizati ...

MAPK13

Mitogen-activated protein kinase 13, also known as stress-activated protein kinase 4, is an enzyme that in humans is encoded by the MAPK13 gene.

MAPK14

Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. MAPK14 encodes the p38a mitogen-activated protein kinase mark, which is the prototype member of the family of P38 MAPK. P. 38 MAPKs ...

MARCKS

Myristoylated alanine-rich C-kinase substrate is a protein that in humans is encoded by the MARCKS gene. It plays important roles in cell shape, cell motility, secretion, transmembrane transport, regulation of the cell cycle, and neural developme ...

MCM3

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins MCM that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component ...

MDC1

Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene located on the short arm of chromosome 6. MDC1 protein is a regulator of the Intra-S phase and the G2/M cell cycle checkpoint ...

MDFI

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA ...

MDN1

Model organisms have been used in the study of MDN1 function. A conditional knockout mouse line, called Mdn1 tm1aKOMPWtsi was generated as part of the International Knockout Mouse Consortium program - a high-throughput mutagenesis project to gene ...

ME1 (gene)

NADP-dependent malic enzyme is a protein that in humans is encoded by the ME1 gene. This gene encodes cytosolic NADP -dependent enzyme that generates NADPH for the biosynthesis of fatty acids. The activity of this enzyme, the reversible oxidative ...

MEP1A

Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that in humans is encoded by the MEP1A gene. The MEP1A locus is on chromosome 6p in humans and on chromosome 17 in mice.

Metabotropic glutamate receptor 1

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be ...

Metabotropic glutamate receptor 4

Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III metabotropic glutamate receptor family. Group III receptors are linked to inhibition of camp casc ...

MLIP (gene)

The function of MLIP is not known but it has been suggested that it may have a role in the growth of the heart and heart disease. There is some evidence that MLIP may be involved in maintaining cardiac homeostasis and in the initial reaction to c ...

MMS22L

Methyl methanesulfonate-sensitivity protein 22-like also known as MMS22-like, DNA repair protein is a protein that in humans is encoded by the MMS22L gene.

MOCS1

Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene. Both copies of the gene defective in patients with molybdenum cofactor deficiency, type A. Bi ...

Monocarboxylate transporter 10

Monocarboxylate transporter 10, also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 and solute carrier family 16 member 10, is a protein that in humans is encoded by the SLC16A10 gene. SLC16A10 is a member of the s ...

MRAP2

Melanocortin 2 receptor accessory protein 2 is a protein that in humans is encoded by the MRAP2 gene. MRAP2 interacts directly with melanocortin 4 receptor. Knockout of the gene Mrap2 in mice leads to severe obesity. In addition, a rare mutation ...

MRPS18A

28S ribosomal protein S18a, mitochondrial is a protein that in humans is encoded by the MRPS18A gene. Mitochondrial ribosomal protein of mammals is encoded by nuclear genes and help in protein synthesis in the mitochondria. Mitoribosomes mitochon ...

MRPS18B

28S ribosomal protein S18b, mitochondrial is a protein that in humans is encoded by the MRPS18B gene. Mitochondrial ribosomal protein of mammals is encoded by nuclear genes and help in protein synthesis in the mitochondria. Mitoribosomes mitochon ...

MSH5

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity ...

MTCH1

Mitochondrial carrier homolog 1, also referred to as presenilin 1-associated protein, is a protein that in humans is encoded by the MTCH1 gene on chromosome 6. MTCH1 is a proapoptotic mitochondrial protein potentially involved in Alzheimer’s disease.

MTHFD1L

Monofunctional C1-tetrahydrofolate synthase, mitochondrial also known as formyltetrahydrofolate synthetase, is an enzyme that in humans is encoded by the MTHFD1L gene 1-like).

MTRF1L

Mitochondrial translational release factor 1-like is a protein that in humans is encoded by the MTRF1L gene. Mitochondrial DNA encodes 13 proteins that play an important role in the respiratory chain, while all proteins involved in mitochondrial ...

MYLIP

Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene. MYLIP is also known as the idol of the "Inducible Degrader of the LDL receptor" based on its involvement in the regu ...

MYLK4

Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain kinase family of serine/threonine-specific protein kinases that phosphorylate the regulatory li ...

MYO6

Myosin VI, also known as MYO6, is a protein. It has been found in humans, mice, fruit flies, and nematodes.

NAD(P)H dehydrogenase, quinone 2

NADH dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions. Its mechanism of reduction is via a covalently ...

NDUFAF4

NADH:ubiquinone oxidoreductase complex assembly factor 4, also known as Hormone-regulated proliferation-associated protein of 20 kDa, or C6orf66 is a protein that in humans is encoded by the NDUFAF4 gene. NDUFAF4 is a mitochondrial assembly prote ...

NFKBIE

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene.

NOX3

NADPH oxidases, such as NOX3, are plasma membrane-associated enzymes found in many cell types. They catalyze the production of superoxide by a 1-electron reduction of oxygen, using NADPH as the electron donor.

NRN1

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be ind ...

Nucleoporin 43

Nucleoporin 43 is a protein that in humans is encoded by the NUP43 gene. Bidirectional transport of macromolecules between the nucleus and the cytoplasm is accomplished through nuclear pore complexes NPCs embedded in the nuclear envelope. NPCs co ...

Nucleoporin 153

Nucleoporin 153 is a protein which in humans is encoded by the NUP153 gene. It is an essential component of the basket of nuclear pore complexes in vertebrates, and required for the anchoring of NPCs. It also acts as the docking site of an import ...

NUDT3

Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene. NUDT3 belongs to the mutt, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside path ...

Oct-4

Oct-4, also known as POU5F1, is a protein that in humans is encoded by the POU5F1 gene. Oct-4 is a homeodomain transcription factor of the POU family. It is critically involved in the self-renewal of undifferentiated embryonic stem cells. As such ...

OR2A4

Olfactory receptor 2A4 is a protein that in humans is encoded by the OR2A4 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2B2

Olfactory receptor 2B2 is a protein that in humans is encoded by the OR2B2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2B3

Putative olfactory receptor 2B3 is a protein that in humans is encoded by the OR2B3 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory re ...

OR2B6

Olfactory receptor 2B6 is a protein that in humans is encoded by the OR2B6 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2H1

Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2H2

Olfactory receptor 2H2 is a protein that in humans is encoded by the OR2H2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2J1

Olfactory receptor 2J1 is a protein that in humans is encoded by the OR2J1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

OR2J2

Olfactory receptor 2J2 is a protein that in humans is encoded by the OR2J2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

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P38 mitogen-activated protein kinases

Phosphoglycerate kinase

T-cell activation RhoGTPase activatin ..

Thiopurine methyltransferase

Transcription initiation protein SPT3 ..

Transmembrane protein 242

TREM1

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