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ZNF16

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene. The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in the immediate area to ...

                                               

ABCA1

ATP-binding cassette transporter ABCA1, also known as the cholesterol efflux regulatory protein is a protein which in humans is encoded by the ABCA1 gene. This transporter is a major regulator of cellular cholesterol and phospholipid homeostasis.

                                               

ABCA2

ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene. Membrane-associated proteins encoded by this gene is a member of the superfamily of ATP-binding cassette transporters the ABC. ABC proteins trans ...

                                               

ABO (gene)

Histo-blood group ABO system transferase is an enzyme with glycosyltransferase activity, which is encoded by the ABO gene in humans. It is ubiquitously expressed in many tissues and cell types. ABO determines the ABO blood group of an individual ...

                                               

ACO1

The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein bind ...

                                               

ADAMTS13

ADAMTS13 - also known as von Willebrand factor-cleaving protease - is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor, a large protein involved in blood clotting. It is secreted into the blood and degrades large vWf mu ...

                                               

ADAMTSL1

ADAMTS-like protein 1 is a protein that in humans is encoded by the ADAMTSL1 gene. This gene encodes a secreted protein resembling members of the ADAMTS in the disintegrin and metalloproteinase with thrombospondin motif family. This protein lacks ...

                                               

Adenylate kinase 1

This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Ce ...

                                               

AGPAT2

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholip ...

                                               

AGTPBP1 (gene)

NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.

                                               

AK3

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.

                                               

ALDH1B1

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of ...

                                               

ANAPC2

Anaphase-promoting complex subunit 2 is an enzyme that in humans is encoded by the ANAPC2 gene. A large protein complex called the anaphase-promoting complex APC, or cyclosome, promotes metaphase-anaphase transition in ubiquitinating its specific ...

                                               

Angiopoietin-related protein 2

Angiopoietin-like protein 2 maintains tissue homeostasis by promoting adaptive inflammation and subsequent tissue reconstruction, whereas an excess of ANGPTL2 activation induced by prolonged stress promotes the breakdown of tissue homeostasis due ...

                                               

ANKRD15

KN motif and ankyrin repeat domain-containing protein 1 is a protein that in humans is encoded by the KANK1 gene. This gene encodes a protein containing four ankyrin repeat domains in its C-Terminus. The proposed role for this protein in tumorige ...

                                               

Annexin A1

Annexin A1 belongs to the annexin family of Ca 2+ -dependent phospholipid-binding proteins that have a molecular weight of approximately 35.000 to 40.000 Dalton and are preferentially located on the cytosolic face of the plasma membrane. Annexin ...

                                               

ANP32B

Acidic leucine-rich nuclear phosphoprotein 32 family member B also known as "acidic protein rich in leucines" is a protein that in humans is encoded by the ANP32B gene. The APR is also an abbreviation is used for an entirely different protein, TN ...

                                               

APBA1

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimers disease amyloid precursor protein APP. It stabilises APP and inhibits production of proteolytic APP fragme ...

                                               

Aprataxin

Aprataxin is a protein that in humans is encoded by the APTX gene. This gene encodes a member of the histidine triad superfamily of hit, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein ...

                                               

Argininosuccinate synthetase 1

Argininosuccinate synthetase is an enzyme that in humans is encoded by the ASS1 gene. The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthesis his way. There are approximately 10 to 14 copies of this gene inclu ...

                                               

ASB6

Ankyrin repeat and SOCS box protein 6 is a protein that in humans is encoded by the ASB6 gene. The protein encoded by this gene belongs to the family of ankyrin repeat proteins that along with four other protein families, contain a C-terminal mot ...

                                               

ATP6V1G1

V-type proton ATPase subunit G 1 is an enzyme that in humans is encoded by the ATP6V1G1 gene. This gene encodes a component vacuolar ATPase V-ATPase, a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPa ...

                                               

B4GALT1

Beta-1.4-galactosyltransferase 1 is an enzyme that in humans is encoded by the B4GALT1 gene. This gene is one of seven beta 1.4-galactosyltransferase genes beta4GalT. They encode a second type of membrane-bound glycoproteins, which seem to have e ...

                                               

BAAT

Bile acid-CoA:amino acid N-acyltransferase is an enzyme that in humans is encoded by the BAAT gene. The protein encoded by this gene enzyme in the liver that catalyze the transfer of bile acids in the fragment of the acyl-COA complex thioethers o ...

                                               

Barx homeobox 1

This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The prote ...

                                               

BICD2

Protein bicaudal D homolog 2 is a protein that in humans is encoded by the BICD2 gene. This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. He was involved in dynein-mediated, minus end-directed motil ...

                                               

Bromodomain-containing protein 3

Bromodomain-containing protein 3 also known as RING3-like protein is a protein that in humans is encoded by the BRD3 gene. This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene ...

                                               

C9orf3

Chromosome 9 open reading frame 3 also known as aminopeptidase O is an enzyme which in humans is encoded by the C9ORF3 gene. The protein encoded by this gene is an aminopeptidase which is most closely related in sequence to leukotriene A4 hydrola ...

                                               

C9orf50

Chromosome 9 open reading frame 50 is a protein that in humans is encoded by the C9orf50 gene. C9orf50 has one other known alias, FLJ35803. In humans the gene coding sequence is 10.051 base pairs long, transcribing an mRNA of 1.624 bases that enc ...

                                               

C9orf64

C9orf64 is a gene located on chromosome 9, that in humans encodes the protein queuosine salvage protein. The function and biological process of the queuosine salvage protein is not well understood by the scientific community, but some evidence fr ...

                                               

C9orf72

C9orf72 is a protein which in humans is encoded by the gene C9orf72. C9orf72 gene located on the short arm of chromosome 9 P open reading frame 72, from base pair to base pair 27.546.542 27.573.863. Its cytogenetic location 9p21.2. Protein is fou ...

                                               

Carbonic anhydrase 9

Carbonic anhydrase IX is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase isoforms found in humans and is a transmembrane dimeric metalloenzyme with an extracellular active site that facilitates acid sec ...

                                               

Carnitine O-acetyltransferase

Carnitine O-acetyltransferase also called carnitine acetyltransferase is an enzyme that encoded by the CRAT gene that catalyzes the chemical reaction acetyl-CoA + carnitine ⇌ {\displaystyle \rightleftharpoons } CoA + acetylcarnitine where the ace ...

                                               

Cathepsin L2

Cathepsin L2, also known as cathepsin V and encoded by the CTSV gene, is a human gene. The protein encoded by this gene is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in the physiology o ...

                                               

CD72

CD72, also known in murine biology as Lyb-2, is a protein active in the immune system of animals. It consists of two identical halves, each of about 39-43 kD, and is a C-type lectin. Its primarily locus of expression is B-cells, where it appears ...

                                               

CDC26

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex APC. APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiqui ...

                                               

CDK5RAP2

CDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene. It has necessary roles in the formation and stability of microtubules from the centrosome and has been found to be linked to human brain siz ...

                                               

CDKN2B

Cyclin-dependent kinase 4 inhibitor B also known as multiple tumor suppressor 2 or p15 INK4b is a protein that is encoded by the CDKN2B gene in humans.

                                               

CDKN2BAS

CDKN2B-AS, also known as ANRIL is a long non-coding RNA consisting of 19 exons, spanning 126.3kb in the genome, and its spliced product is a 3834bp RNA. It is located within the p15/CDKN2B-p16/CDKN2A-p14/ARF gene cluster, in the antisense directi ...

                                               

CFAP157

Cilia and flagella associated protein 157 also known as chromosome 9 open reading frame 117 is a protein that in humans is encoded by the CFAP157 gene. Gene CFAP157 is "specifically during spermatogenesis for the morphogenesis of the flagellum an ...

                                               

CHMP5

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein CHMP family. These proteins are components of ESCRT-III endosomal sorting complex required for transport III, a complex involved in degradation of surface recept ...

                                               

Chromosome 9 open reading frame 43

Chromosome 9 open reading frame 43 is a protein that in humans is encoded by the C9orf43 gene. The gene is also known as MGC17358 and LOC257169. C9orf43 contains DUF 4647 and a polyglutamine repeat region although protein function is not well und ...

                                               

CIZ1

The protein encoded by this gene is a zinc finger DNA binding transcription factor that interacts with CIP1 p21 / CDKN1A, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1.

                                               

CKS2

Cyclin-dependent kinases regulatory subunit 2 is a protein that in humans is encoded by the CKS2 gene. CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological functions. In the CKS2 mRNA i ...

                                               

CNTRL

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110. This gene encodes a protein required for MT growing from the centrosome to function as an organizing center for microtubules. The gene product ...

                                               

Cofactor of BRCA1

NELF-B is a subunit of negative elongation factor NELF, which also includes NELF-A WHSC2, MIM 606026, either NELF-C or NELF-D TH1L, MIM 605297, and NELF-E RDBP, MIM 154040. NELF acts with DRB sensitivity-inducing factor DSIF, a heterodimer of SPT ...

                                               

Collagen, type V, alpha 1

Collagen alpha-1 chain is a protein that in humans is encoded by the COL5A1 gene. This gene encodes the alpha chain for one of the low abundance fibrillar collagens. The fibrillar collagen molecules are trimers that can consist of one or more typ ...

                                               

Collagen, type XV, alpha 1

Collagen alpha-1 chain is a protein that in humans is encoded by the COL15A1 gene. This gene encodes the alpha chain of type XV collagen, a member of the family of collagen fibrils-associated FACIT collagens with interrupted helices. Type XV coll ...

                                               

Collagen, type XXVII, alpha 1

Collagen alpha-1 chain is a protein that in humans is encoded by the COL27A1 gene. COL27A1, the type XXVII collagen. He was discovered by James leg. This gene appears to be included in cartilage, the eye, and ear. Type XXVII collagen refers to th ...

                                               

Complement component 5

Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is split into C5A and C5b: C5a plays an important role in chemotaxis. C5b forms the first part of the co ...

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