Blog page 89



                                               

RIG-I

RIG-I is a RIG-I-like receptor dsRNA helicase enzyme that is encoded by the DDX58 gene. RIG-I is part of the RIG-I-like receptor family, which also includes MDA5 and LGP2, and functions as a pattern recognition receptor that is a sensor for virus ...

                                               

RMI1

During meiosis in budding yeast Saccharomyces cerevisiae, TOP3 a type I topoisomerase and its accessory factor RMI1 form a heterodimer that functions to allow passage of one DNA single strand through another. The TOP3-RMI1 heterodimer associates ...

                                               

RNF20

E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with the BRE 1 of S. cerevisiae. Yeast BRE 1 is a ubiquitin ligase required for ubiquitination of histo ...

                                               

RNF38

RING finger protein 38 is a protein that in humans is encoded by the RNF38 gene. This gene encodes a protein with a coiled coil motif and a ring-H2 motif C3H2C2 at its carboxy-end. The ring motif is a zinc-binding domain found in a large set of p ...

                                               

RNF183

                                               

RRAGA

                                               

SARDH

                                               

SEC16A

                                               

SEC61B

Protein transport protein Sec61 subunit beta is a protein that in humans is encoded by the SEC61B gene. The Sec61 complex is the Central component of the protein translocation apparatus in the endoplasmic reticulum membrane er. Oligomers of the S ...

                                               

SECISBP2

The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence SECIS, a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in ...

                                               

Serine C-palmitoyltransferase

In enzymology, a serine C-palmitoyltransferase is an enzyme that catalyzes the chemical reaction: palmitoyl-CoA + L-serine ⇌ {\displaystyle \rightleftharpoons } CoA + 3-dehydro-D-sphinganine + CO2 Thus, the two substrates of this enzyme Palmitoyl ...

                                               

SETX

Probable helicase senataxin is an enzyme that in humans is encoded by the SETX gene. This gene encodes a protein named for its homology to the Sen1p protein of fungi which has the activity of RNA encoded helicase domain in the C-terminal end of t ...

                                               

SH2D3C

Sh2d3c is a gene on human chromosome 9 that encodes an SH2 domain containing protein known as NSP3. The mouse homologue is found on chromosome 2. The NSP Novel SH2-containing Protein family of proteins contains three members, NSP1, NSP2, and NSP3 ...

                                               

SH3GL2

                                               

SH3GLB2

                                               

SHB (gene)

                                               

SHC3

                                               

Sigma-1 receptor

The sigma-1 receptor, one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum that modulates calcium signaling through the IP3 receptor. In humans, the σ 1 receptor is encoded by the SIGMAR1 gene. In the σ 1 recept ...

                                               

SIT1

                                               

SMARCA2

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of cert ...

                                               

SMC2

Structural maintenance of chromosomes protein 2 also known as chromosome-associated protein E is a protein that in humans is encoded by the SMC2 gene. SMC-2 is a subunit of condensin I and II, large protein complexes involved in condensation of c ...

                                               

SMC5

Structural maintenance of chromosomes protein 5 is a protein encoded by the SMC5 gene in human. Structural maintenance of chromosomes on the complex mechanisms involved in the dynamics of chromatin is unknown and new discoveries shed light on dif ...

                                               

SNAPC3

                                               

SNAPC4

Model organisms have been used in the study of SNAPC4 function. A conditional knockout mouse line, called Snapc4 tm1aKOMPWtsi was generated as part of the International Knockout Mouse Consortium program - a high-throughput mutagenesis project to ...

                                               

Sperm-associated antigen 8

Sperm-associated antigen 8 is a protein that in humans is encoded by the SPAG8 gene. The ratio of anti-sperm antibodies in cases of unexplained infertility implies a role of these antibodies in blocking fertilization. Improving the diagnosis and ...

                                               

SPIN1

                                               

ST6GALNAC4

ST6 -N-acetylgalactosaminide alpha-2.6-sialyltransferase 4, also known as sialyltransferase 3C or sialyltransferase 7D is a sialyltransferase enzyme that in humans is encoded by the ST6GALNAC4 gene.

                                               

ST6GALNAC6

                                               

STOML2

                                               

STRBP

                                               

STX17

                                               

STXBP1

Syntaxin-binding protein 1 is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmemb ...

                                               

SURF1

Surfeit locus protein 1 is a protein that in humans is encoded by the SURF1 gene. The protein encoded by SURF1 is a component of the mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex, which is involved in ...

                                               

SURF2

                                               

SURF4

Surfeit locus protein 4 is a protein that in humans is encoded by the SURF4 gene. This gene is located in the surfeit gene cluster, which is composed of very tightly linked genes "household", which do not share sequence similarity. The encoded pr ...

                                               

SURF6

Surfeit locus protein 6 is a protein that in humans is encoded by the SURF6 gene. This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a ho ...

                                               

Surfeit

Surfeit is a human gene cluster that consists of a group of very tightly linked genes on chromosome 9 that do not share sequence similarity. Genes in this cluster are numbered 1 through 6: SURF1, SURF2, SURF3, SURF4, SURF5, and SURF6.

                                               

TAL2

                                               

Talin (protein)

Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell–substratum contact and, in lymphocytes, at cell–cell contacts. Discovered in 1983 by Keith Burridge and colleagues, talin is a ubiquitous cytosolic protein that ...

                                               

TDRD7

Tudor domain-containing protein 7 is a protein that in humans is encoded by the TDRD7 gene. In melanocytic cells TDRD7 gene expression may be regulated by MITF.

                                               

Tenascin C

Tenascin C is a glycoprotein that in humans is encoded by the TNC gene. It is expressed in the extracellular matrix of various tissues during development, disease or injury, and in restricted neurogenic areas of the central nervous system. Tenasc ...

                                               

TESK1

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases ...

                                               

Tetratricopeptide repeat domain 16 isoform 1

Tetratricopeptide repeat domain 16 is an uncharacterized protein that in humans is encoded by the gene TTC16. Another alias for this gene is TPR repeat protein 16, but this is not commonly used. TTC16 is one of many proteins that contain tetratri ...

                                               

Tetratricopeptide repeat protein 39B

Tetratricopeptide repeat protein 39B is a protein that in humans is encoded by the TTC39B gene. TTC39B is also known as C9orf52 or FLJ33868. The main feature within tetratricopeptide repeat 39B is the domain of unknown function 3808, spanning the ...

                                               

TEX10

                                               

TGF beta receptor 1

Transforming growth factor beta receptor I is a membrane-bound receptor protein for the TGF beta superfamily of signaling ligands. TGFBR1 is its human gene.

                                               

Tight junction protein 2

Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene. Close contact with TJPs proteins belong to a family of membrane-associated kinases disodium guanylate, and disodium MAGUK homologues, which are involved in the o ...

                                               

TLE1

                                               

TLE4

                                               

TLN1

Talin-1 is a protein that in humans is encoded by the TLN1 gene. Talin-1 is ubiquitously expressed, and is localized to costamere structures in cardiac and skeletal muscle cells, and to focal adhesions in smooth muscle and non-muscle cells. Talin ...

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